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Participants/Project AbstractsSummer 2006 Bioanalytical Science REU Participants
UCR Student - Rebecca Austin INTERACTIONS AND STRUCTURE OF NUCLEIC ACIDS WITH DIFFERENT CATIONS Rebecca Austin, Jianshuang Wang, Qichun Zhang, and Pingyun Feng PhDDepartment of Chemistry, University of California - Riverside , UCR 92521 Nucleic acids can interact with different cations that are either organic or inorganic. Through electrostatic interactions, hydrogen bonding and other weaker interactions between nucleic acids and these cations, new compounds can be formed that have different geometries and organization. The structures of new compounds can be probed by X-ray diffraction analysis and spectroscopic techniques. Through the study of structural features and packing symmetries of the new compounds, the influence of cations with different hydrophilic and hydrophobic domains and charge density on the resulting composite structures will be understood. This work is aimed at an improved understanding of behaviors of nuleic acid under perturbation by various chemical species. << Back to Participants/Project Abstracts Main Page
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