Peer-reviewed Publications

Holloway, L. R.; Bogie, P. M.; Lyon, Y.; Julian, R. R.; Hooley, R. J.
"Stereoselective Postassembly CH Oxidation of Self-Assembled Metal-Ligand Cage Complexes" Inorg. Chem. 2017
, DOI:10.1021/acs.inorgchem.7b01958

Liu, Y.; Perez, L.; Gill, A. D.; Mettry, M.; Li, L.; Wang, Y.; Hooley, R. J.*; Zhong, W.*
"Site-Selective Sensing of Histone Methylation Enzyme Activity via an Arrayed Supramolecular Tandem Assay" J. Am. Chem. Soc. 2017
, DOI:10.1021/jacs.7b05002

Bogie, P. M.; Holloway, L. R.; Lyon, Y.; Julian, R. R.; Hooley, R. J.
"Metal-Selective Coordination and Enhanced Fluorescence of a Self-Assembling Ligand Scaffold" Supramol. Chem. 2017, DOI:10.1080/10610278.2017.1347261

Perez, L.; Mettry, M.; Hinman, S. S.; Byers, S. R.; McKeating, K. S.; Caulkins, B. G.; Cheng, Q.; Hooley, R. J.
"Selective Protein Recognition in Supported Lipid Bilayer Arrays by Tailored, Dual-Mode Deep Cavitand Host" Soft Matter 2017,13, 3966-3974.
DOI:10.1039/C7SM00192D

Liu, Y.; Perez, L.; Mettry, M.; Gill, A. D.; Byers, S. R.; Easley, C. J.; Bardeen, C. J.; Zhong, W.;* Hooley, R. J.*
"Site Selective Reading of Epigenetic Markers by a Dual-Mode Synthetic Receptor Array" Chem. Sci. 2017, 8, DOI:10.1039/C7SC00865A

Wiley, C.A.; Holloway, L.R.; Miller, T.F.; Lyon, Y.; Julian, R.R.; Hooley, R. J.
"Electronic Effects on Narcissistic Self-Sorting in Multicomponent Self-Assembly of Fe-Iminopyridine meso-Helicates" Inorg. Chem. 2016, 55, 9805-9815
DOI: 10.1021/acs.inorgchem.6b01644

Liu, Y.; Perez, L.; Mettry, M.; Easley, C.J.; Hooley, R. J.*; Zhong, W.*
"A Self-Aggregating Deep Cavitand Acts as a Fluorescence Displacement Sensor for Lysine Methylation" J. Am. Chem. Soc. 2016, 138, 10746–10749.

DOI: 10.1021/jacs.6b05897

Mettry, M.; Moehlig, M. P.; Gill, A.; Hooley, R. J.
"Alkane Oxidation Catalyzed by Self-Folded Multi-Iron Complex" Supramol. Chem, 2016, 2855. 120-128.
DOI: 10.1080/10610278.2016.1177184

Holloway, L. R.; McGarraugh, H. H.; Young, M. C.; Sontising, W.; Beran, G. J. O.; Hooley, R. J.
"Structural Switching in Self-Assembled Metal-Ligand Helicate Complexes via Ligand-Centered Reactions"
Chem. Sci., 2016, 7, 4423-4427
DOI: 10.1039/C6SC01038E

Perez, L.; Ghang, Y-J; Williams P. B.; Wang, Y.; Cheng, Q.; Hooley, R. J.
"Cell and Protein Recognition at a Supported Bilayer Interface via In Situ Cavitand-Mediated Functional Polymer Growth"
Langmuir. 2015, 31, 11152-11157 DOI: 10.1021/acs.langmuir.5b03124

Holloway, L. R.; Young, M. C.; Beran, G. J. O.; Hooley, R. J.
"High Fidelity Sorting of Remarkably Similar Components via Metal-Mediated Assembly"
Chem. Sci. 2015, 6, 4801-4806 DOI: 10.1039/C5SC01689D

Johnson, A.M.; Wiley, C. A.; Young, M. C.; Zhang, X.; Lyon, Y.; Julian, R. R.; Hooley, R. J.
"Narcissistic Self-Sorting in Self-Assembled Cages of Rare Earth Metals and Rigid Ligands" Angew. Chem. Int. Ed. 2015, 54, 5641-5645
DOI: 10.1002/anie.201500400

Mettry, M.; Moehlig, M. P.; Hooley, R. J.
"Synthesis, Guest Binding, and Metal Coordination of Functionalized Self-Folding Deep Cavitands"
Org. lett. 2015, 17, 1497-1500 DOI: 10.1021/acs.orglett.5b00383

Ghang, Y-J.; Perez, L.; Morgan, M.; Si, F.; Hamdy, O.; Beecher, C.; Larive, C.; Julian, R.; Zhong, W.; Chenga, Q.; Hooley, R. J.
"Anionic deep cavitands enable the adhesion of unmodified proteins at a membrane bilayer"
Soft Matter. 2014,10, 9651-9656 DOI: 10.1039/c4sm02347a

Young, M. C.; Holloway, R. L.; Johnson, A. M.; Hooley, R. J.
"A Supramolecular Sorting Hat: Stereocontrol in Metal–Ligand Self-Assembly by Complementary Hydrogen Bonding"

Angew. Chem. Int. Ed. 2014, 53,9832 DOI: 10.1002/anie.20140524

Ghang, Y-J.; Lloyd, J.; Moehlig, M.; Arguelles, J.; Mettry, M.; Zhang, X.; Julian, R.; Cheng, Q.; Hooley, R. J.
"Labeled Protein Recognition at a Membrane Bilayer Interface by Embedded Synthetic Receptors"Langmuir, 2014, 30, 10161. DOI: 10.1021/la502629d

Hooley, R. J.; Gavette, J.; Mettry, M.; Ajami, D.; Rebek, J., Jr.
"Unusual Orientation and Reactivity of Alkyl Halides in Water-Soluble Cavitands"Chem. Sci., 2014, 5, 4382. DOI: 10.1039/C4SC01316F

Young, M. C.; Liew, E.; Hooley, R. J.
"Colorimetric Barbiturate Sensing with Hybrid Spin Crossover Assemblies" Chem. Commun., 2014, 50, 5043. DOI: 10.1039/C4CC01805B

Young, M. C.; Johnson, A. M.; Hooley, R. J.
"Self-Promoted Post-Synthetic Modification of Metal-Ligand M2L3 Mesocates" Chem. Commun., 2014, 50, 1378. DOI: 10.1039/C3CC48444K

Li, V.; Ghang, Y.-J.; Hooley, R. J.; Williams, T.
"Non-Covalent Self Assembly Controls the Relaxivity of Magnetically Active Guests" Chem. Commun., 2014, 50, 1375. DOI: 10.1039/C3CC48389D

Johnson, A. M.; Young, M. C.; Zhang, X.; Julian, R. R.; Hooley, R. J.
"Cooperative Thermodynamic Control of Selectivity in the Self-Assembly of Rare Earth Metal-Ligand Helices" J. Am. Chem. Soc., 2013, 135, 17723. DOI: 10.1021/ja409882k

Hong, J.; Djernes, K. E.; Lee, I.; Hooley, R. J.; Zaera, F.
"Heterogeneous Catalyst for the Selective Oxidation of Unactivated Hydrocarbons Based on a Tethered Metal-Coordinated
Cavitand" ACS Catal., 2013, 3, 2154. DOI: 10.1021/cs400471b

Young, M. C.; Liew, E.; Ashby, J.; McCoy, K. E.; Hooley, R. J.
"Spin State Modulation of Iron Spin Crossover Complexes Via Hydrogen-Bonding Self-Assembly" Chem. Commun., 2013, 49, 6331. DOI: 10.1039/C3CC42851F

Ghang, Y-J.; Schramm, M. P.; Zhang, F.; Acey, R. A.; David, C. N.; Wilson, E. H.; Wang, Y.; Cheng, Q.; Hooley, R. J.
"Selective Cavitand-Mediated Endocytosis of Targeted Imaging Agents into Live Cells" J. Am. Chem. Soc., 2013, 135, 7090. DOI: 10.1021/ja401273g

Johnson, A. M.; Young, M. C.; Hooley, R. J.
"Reversible Multicomponent Self-Assembly Mediated By Bismuth Ions" Dalton Trans., 2013, 42, 8394. DOI: 10.1039/C3DT50578B

Young, M. C.; Johnson, A. M.; Gamboa, A. S.; Hooley, R. J.
"Achiral Endohedral Functionality Provides Stereochemical Control in Fe(II)-Based Self-Assemblies" Chem. Commun., 2013, 49, 1627. DOI: 10.1039/C3CC37912D

Djernes, K. E.; Padilla, M.; Mettry, M.; Young, M. C.; Hooley, R. J.
"Hydrocarbon Oxidation Catalyzed by Self-folded Metal-coordinated Cavitands" Chem. Commun., 2012, 48, 11576. DOI: 10.1039/C2CC36236H

Liu, Y.; Young, M. C.; Moshe, O.; Cheng, Q.; Hooley, R. J.
"A Membrane-Bound Synthetic Receptor Promotes Growth of a Polymeric Coating at the Bilayer–Water Interface" Angew. Chem. Int. Ed., 2012, 30, 7748; Angew. Chem., 2012, 124, 7868-7871. (Listed as a Very Important Publication) DOI: 10.1002/anie.201202635

Moehlig, A. R., Djernes, K. E., Krishnan, V. M., Hooley, R. J.
"Cytosine Derivatives Form Hemiprotonated Dimers in Solution and the Gas Phase" Org. Lett., 2012, 14, 2560. DOI: 10.1021/ol300861r

Djernes, K. E.; Moshe, O.; Mettry, M.; Richards, D. D.; Hooley, R. J.
“Metal-coordinated Water Soluble Cavitands act as C-H Oxidation Catalysts” Org. Lett., 2012, 14, 788. DOI: 10.1021/ol203243j

Liu, Y.; Taira, T.; Young, M. C.; Ajami, D.; Rebek, J., Jr.; Cheng, Q.; Hooley, R. J.
“Protein Recognition by a Self-Assembled Deep Cavitand Monolayer on a Gold Substrate” Langmuir, 2012, 28, 1391. DOI: 10.1021/la2039398

Johnson, A. M.; Moshe, O.; Gamboa, A. S.; Langloss, B. W.; Limtiaco, J. F. K.; Larive, C. K; Hooley, R. J.
“Synthesis and Properties of Metal-Ligand Complexes with Endohedral Amine Functionality” Inorg. Chem., 2011, 50, 9430. DOI: 10.1021/ic201092s

Johnson, A. M.; Hooley, R. J.
“Steric Effects Control Self-Sorting in Self-Assembled Clusters” Inorg. Chem., 2011, 50, 4671. DOI: 10.1021/ic2001688

Liu, R.; Liao, P.; Zheng, Z.; Hooley, R. J.; Feng, P.
“A Water-soluble Deep Cavitand Acts as a Release Trigger for a Supramolecular Nanocap” Chem. Mater. 2010, 22, 5797. DOI: 10.1021/cm102298y

Liao, P.; Langloss, B. W.; Johnson, A. M.; Knudsen, E. R.; Tham, F. S.; Julian, R. R., Hooley, R. J.
“Two-Component Control of Guest Binding in a Self-Assembled Cage Molecule” Chem. Commun., 2010, 46, 4932. DOI: 10.1039/C0CC00234H

Liu, Y.; Liao, P.; Cheng, Q.; Hooley, R. J.
“Protein and Small Molecule Recognition Properties of Deep Cavitands in a Supported Lipid Membrane Determined by
Calcination-Enhanced SPR Spectroscopy” J. Am. Chem. Soc., 2010, 132, 10383. DOI: 10.1021/ja102252d

Education-Related Publications

Meyet, C.; Hooley, R. J.
"Organic Chemistry and Your Cellphone: Organic Light-Emitting Diodes" NSF National Center for Case Study Teaching in Science, 2013. Link

Post-Doctoral Work

Ajami, D.; Kamioka, S.; Sather, A. C.; Hooley, R. J.; Rebek, J., Jr.
"Autocatalysis and organocatalysis with Kemp's triacid compounds" Heterocycles, 2011, 82, 1203. DOI: 10.3987/COM-10-S(E)31

Hooley, R. J.; Rebek, J., Jr.
“Chemistry and Catalysis in Functional Cavitands” Chem. Biol., 2009, 16, 255. DOI: 10.1016/j.chembiol.2008.09.015

Tran, C. D.; Mejac, I.; Rebek, J., Jr; Hooley, R. J.
“Gas Chromatographic Separation of Isotopic Molecules Using a Novel Cavitand-impregnated Stationary Phase” Anal. Chem., 2009, 81, 1244. DOI: 10.1021/ac8021423

Hooley, R. J.; Shenoy, S. R.; Rebek, J., Jr.
“Electronic and Steric Effects in Binding of Deep Cavitands” Org. Lett., 2008, 10, 5397. DOI: 10.1021/ol8022775

Hooley, R. J.; Restorp, P.; Rebek, J., Jr.
“A Cavitand with a Fluorous Rim acts as an Amine Receptor” Chem. Commun., 2008, 6291. DOI: 10.1039/B814069C

Lledó, A.; Hooley, R. J.; Rebek, J., Jr.
“Recognition of Guests by Water-stabilized Cavitand Hosts” Org. Lett., 2008, 10, 3669. DOI: 10.1021/ol801228b

Podkoscielny, D.; Hooley, R. J.; Rebek, J., Jr.; Kaifer, A. E.
“Ferrocene Derivatives Included in a Water-Soluble Cavitand: Are They Electroinactive?” Org. Lett., 2008, 10, 2865. DOI: 10.1021/ol8010375

Hooley, R. J.; Restorp, P.; Iwasawa, T.; Rebek, J., Jr.
“Cavitands With Introverted Functionality Stabilize Tetrahedral Intermediates” J. Am. Chem. Soc., 2007, 129, 15639. DOI: 10.1021/ja0756366

Hooley, R. J.; Iwasawa, T.; Rebek, J., Jr.
“Detection of Reactive Tetrahedral Intermediates in a Deep Cavitand with an Introverted Functionality” J. Am. Chem. Soc., 2007, 129, 15330. DOI: 10.1021/ja0759343

Hooley, R. J.; Van Anda, H. J.; Rebek, J., Jr.
“Extraction of Hydrophobic Species into a Water-Soluble Synthetic Receptor” J. Am. Chem. Soc., 2007, 129, 13464. DOI: 10.1021/ja0727058

Hooley, R. J.; Rebek, J., Jr.
“A Deep Cavitand Catalyzes the Diels-Alder Reaction of Bound Maleimides” Org. Biomol Chem., 2007, 5, 3631. DOI: 10.1039/B713104F
(Highlighted as a Hot Article, Org. Biomol Chem., 2007, 5, issue 22; highlighted in Chem. Sci., 2007, 4, C90)

Schramm, M. P.; Hooley, R. J.; Rebek, J., Jr.
"Guest Recognition with Micelle-Bound Cavitands" J. Am. Chem. Soc., 2007, 129, 9773. DOI: 10.1021/ja0723378

Iwasawa, T.; Hooley, R. J.; Rebek, J., Jr.
“Stabilization of Labile Carbonyl Addition Intermediates by a Synthetic Receptor” Science, 2007, 317, 493. DOI:10.1126/science.1143272
(Highlighted in Chemical & Engineering News, 85 (32), August 1, 2007)

Hooley, R. J.; Rebek, J., Jr.  
“Self-Complexed Deep Cavitands – Alkyl Chains Coil Into A Nearby Cavity” Org. Lett., 2007, 9, 1179. DOI: 10.1021/ol062782s

Hooley, R. J.; Biros, S. M.; Rebek, J., Jr.
“A Deep, Water-Soluble Cavitand Acts as a Phase-Transfer Catalyst for Hydrophobic Species” Angew. Chem. Int. Ed. Engl., 2006,
45
, 3517; Angew. Chem., 2006, 118, 3597. DOI: 10.1002/anie.200600405

Hooley, R. J.; Van Anda, H. J.; Rebek, J., Jr.
“Cavitands With Revolving Doors Regulate Binding Selectivities and Rates in Water.” J. Am. Chem. Soc., 2006, 128, 3894. DOI: 10.1021/ja058727g

Hooley, R. J.; Biros, S. M.; Rebek, J., Jr.
“Normal Hydrocarbons Writhe and Tumble in a Water-Soluble Cavitand” Chem. Commun., 2006, 509. DOI: 10.1039/B515733A

Hooley, R. J.; Rebek, J., Jr.
“Deep Cavitands Provide Organized Solvation of Reactions” J. Am. Chem. Soc., 2005, 127, 11904. DOI: 10.1021/ja052910s

Predoctoral and Doctoral Work

Semmelhack, M. F.; Hooley, R. J.; Kraml, C. M.
“Synthesis of Plakortone B and Analogs” Org. Lett., 2006, 8, 5203. DOI: 10.1021/ol0618656

Semmelhack, M. F.; Hooley, R. J.
“Palladium-Catalyzed Hydrostannylations of Highly Hindered Acetylenes in Hexane” Tetrahedron Lett., 2003, 44, 5737. DOI: 10.1016/S0040-4039(03)01327-3

Hooley, R. J.; Lee, C. B.
Commentary on “Iron-Catalyzed Cross-Coupling Reactions of Alkyl-Grignard Reagents with Aryl Chlorides, Tosylates
and Triflates” Chemtracts – Organic Chemistry, 2003, 16, 518.

Christlieb, M.; Davies, J. E.; Eames, J.; Hooley, R.; Warren, S. W.
“The Stereoselective Synthesis of Oxetanes; Exploration of a New, Mitsunobu-Style Procedure for the Cyclisation of 1,3-Diols.”
J. Chem. Soc. Perkin Trans. 1, 2001, 2983.
DOI: 10.1039/B106851B

 
 
 
 
 
 
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