The Chang Group

                               

 

        

    Department of Chemistry

 

Graduate Program in Genetics, Genomics and Bioinformatics

 

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The central goal of our work is to understand the fundamental mechanism of biomolecular recognition and binding kinetics using theory and classical mechanical models. Our research involves the development and application of computational methods and theoretical models to address medically and chemically important problems. These methods are of practical importance in studying biomolecular function, and in the design of new molecules that bind strongly to their receptors. Systems of particular interest include existing or potential drug targets, cell signaling complexes and chemical host-guest systems. Our lab also collaborates with experimental groups on and off campus.  

 

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HIV protease

Protein Kinases

 

Tryptophan synthase                                 Enzyme complexes                               

Updated September 2014